Twist Bioscience Corp · Biotech

TWST

Elevated riskNext report: Nov 12 (confirmed)

View price ↗

The short version

A company still losing money with growing sales, with elevated risk.

Going well

Sales up 23% in the latest quarter vs a year ago
Sales up 20% last year
No debt reported

Watch out for

Losing money, losses are large next to sales
2 offering filings in 6 months (may sell new shares)

Money moves

Insiders sold $20.7M in the last 30 days
Institutions cut 1% from their holdings in the quarter ending June 2026 (184 bought, 132 sold)
Held by Ray Dalio (Bridgewater), Cathie Wood (ARK Invest)

Facts from SEC filings, not a recommendation.

What the price means

Price as of Oct 26

$145.34+3.9% that day

Company value: $9.1B; Share price times all shares
Price vs sales: 21.1x; No profit over the last year, so this compares value with sales instead
Cash vs value: 1%; Cash as a share of company value

From TWST's last IEX trade and its SEC filings (profits and sales over the last four quarters). A starting point for research, not a verdict.

The business over time

Last 12 quarters, from SEC filings

Sales, Jun '26

$118.4M+23% vs a year earlier

Sep '23Tap a barJun '26

Last 12 months: $431.8M, up 19% from the 12 months before. Over 5 years, sales grew about 33% a year.

What the price assumes

Your guesses, our math

Move the sliders to your own view of TWST. Starting points are the company's recent numbers (it isn't profitable yet, so the margin starts at a 10% guess).

Sales growth+19% a yearRecently: +19% a yearProfit margin10%Last 12 months: -31.7%P/E at the end15xMany steady companies trade at 12x to 25xShare count change+4% a yearBelow zero means buybacks; above zero means new shares (dilution)

Sales in 5 years$1.0B

Profit in 5 years$103M

Price these guesses point to$20.26-86% vs $145.34 todayAbout -33% a year, before dividends

What today's price needs: with a 10% margin and a 15x P/E, sales would have to grow about 76% a year for 5 years just to match today's price.

Simple math on your guesses, not a forecast or a price target. Real results depend on many things these sliders leave out.

Price

Price chart by TradingView.

Business quality

The checklist Warren Buffett-style investors use. Annual numbers for 2025.

1/6Weak

MissReturn on equity 15%+Earns a lot on the money owners have in the business.-17.0%
PassDebt under half of equityNot relying on borrowed money.No debt reported
MissNet margin 10%+Keeps at least 10 cents of profit from each dollar of sales.-20.6%
MissProfitable every yearSteady profits, not one good year.0 of 9 years
MissFree cash flow positiveBrings in more cash than it spends to run and grow.-$75.6M
MissShare count not growingNot diluting owners. Falling means buybacks.+11.0% in 3 years

Revenue: $376.6M; +20.3% vs prior year
5-year growth: +33.1%/yr; revenue, per year
Total debt: None; 0.00x equity
Current ratio: 3.78x; short-term assets / bills due

From annual reports filed with the SEC. Not in this company's SEC data, so not scored: gross margin 40%+. A checklist is a starting point for research, not a verdict.

Latest quarter

Quarter ended Jun 30, 2026

Reported Aug 3

Revenue: $118.4M; +23.2% YoY
EPS: -$0.56; vs $0.33
Op. margin: -30.6%; +0.8 pts
Gross margin: 52.8%; -0.6 pts
Free cash flow: -$8.6M
Share count: +2.0%; vs a year ago

Insider rating

Last 90 days

14Heavy selling

5 insiders sold $11.0M (not pre-planned)
Pre-planned sales of $10.6M (weaker signal)

50 is neutral. Buying by more insiders, top executives and bigger stakes raises it. Selling lowers it; pre-planned sales count less.

Weekly insider trend

13 weeks agoBoughtSoldThis week

Filing buzz

Last 7 days vs normal

12/ 100

This week: 1
Normal week: 10.0
vs normal: 0.1x

SEC filings of any kind. 50 means a normal week.

Institutional ownership

Steady-1.0%

Institutions cut 1.0% from their holdings. 184 bought, 132 sold.

Shares held by institutions76.4M

Sep '24Jun '26

Safety check

From SEC filings

Share count growthYearly rate, last 3 years

+3.0%

Cash runwayAt last year's cash burn

30 months

Debt to equityLatest balance sheet: debt compared with what owners have

No debt reported

Shares outstandingLatest reported

63M

Why elevated risk

Losing money, losses are large next to sales
2 offering filings in 6 months (may sell new shares)

Earnings reports

Last 12

Next reportNov 12 (confirmed)Announced by the company in a press release ↗

Results filedAug 3
Results filedMay 4
Results filedFeb 2
Results filedJan 12
Results filedNov 14, 2025

Flags and big holders

Offerings 6 months, flags 12 months, holders 90 days

Insider trades

Open-market buys and sells, last 90 days

Bought$00 insiders

Sold$21.7M6 insiders, 3 pre-planned

Insider	Trade	Shares	Avg price	Value	Owns after	Date
Patrick John FinnPresident and COO	Sell	2K	$134.59	$302K	183K	Oct 23Filing ↗
-1.2% of their holdings Not a pre-planned sale Filed 4 days after
Adam LaponisChief Financial Officer	Sell	2K	$156.30	$385K	98K	Oct 9Filing ↗
-2.4% of their holdings Not a pre-planned sale Filed 4 days after
Emily M. LeproustChief Executive Officer	Sell	5K	$202.15	$919K	563K	Oct 5Filing ↗
-0.8% of their holdings $200.44 to $207.46 across 8 trades Pre-planned sale (10b5-1) Also Director Filed 2 days after
Emily M. LeproustChief Executive Officer	Sell	46K	$189.04	$8.8M	567K	Oct 2Filing ↗
-7.6% of their holdings $188.88 to $200.00 across 2 trades Traded Oct 1 to Oct 2 Pre-planned sale (10b5-1) Also Director Filed 3 days after
Robert F. WernerChief Accounting Officer	Sell	1K	$188.88	$280K	43K	Oct 2Filing ↗
-3.3% of their holdings Not a pre-planned sale Filed 3 days after
Adam LaponisChief Financial Officer	Sell	8K	$188.88	$1.5M	101K	Oct 2Filing ↗
-7.4% of their holdings Not a pre-planned sale Filed 3 days after
Paula GreenSVP of Human Resources	Sell	10K	$188.88	$1.9M	107K	Oct 2Filing ↗
-8.6% of their holdings Not a pre-planned sale Filed 3 days after
Patrick John FinnPresident and COO	Sell	26K	$188.88	$4.9M	185K	Oct 2Filing ↗
-12.2% of their holdings Not a pre-planned sale Filed 3 days after
Dennis ChoSee Remarks	Sell	10K	$188.88	$1.8M	64K	Oct 2Filing ↗
-13% of their holdings Not a pre-planned sale Filed 3 days after
Emily M. LeproustChief Executive Officer	Sell	5K	$177.38	$923K	614K	Sep 24Filing ↗
-0.8% of their holdings $175.23 to $184.60 across 10 trades Pre-planned sale (10b5-1) Also Director Filed 1 day after